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  • Hereditary ancestry, collective smoking and you will lung mode one of lady

    Among step one735 women, each 10 pack-years of smoking was associated with a ?0.85% (95% CI ?1.13% to ?0.57%) mean decrement in FEV1 to FVC ratio, a ?48.6 ml (95% CI ?61.6 to ?35.7) mean decrement in FEV1 and a 1.36 (95% CI 1.20 to 1.55) increase in the odds of airflow obstruction. Plots of the relationship of pack-years to FEV1 to FVC ratio showed similarly linear relationships for racial/ethnic groups (see online supplementary figure S1B).

    There was no evidence that the relationship of pack-years to FEV1, FEV1 to FVC ratio or airflow obstruction differed by genetic ancestry among Caucasian, African-American and Hispanic women (table 3). (more…)